Neuromuscular imaging has increasingly become an important tool in the detection and diagnosis of inherited and acquired neuromuscular disease. This book is a groundbreaking radiological and neurological overview of current methods and applications of imagingincluding aspects of neuroimaging and musculoskeletal imagingin patients with inherited, metabolic, and inflammatory muscle diseases. Imaging features are discussed in the context of clincial presentation, histopathology, therapeutic options and differential diagnosis. World leading expert contributors give a comprehensive and didactic review of neuromuscular disorders and available imaging modalities, each illustrated with numerous figures. Topics discussed include:

-Modalities such as ultrasound, CT and MRI

-Muscle anatomy and physiology

-Clinical applications in hereditary and acquired myopathies

-Clinical applications in motor neuron disorders and peripheral nerve imaging

Mike P. Wattjes, MD

Department of Radiology

VU University Medical Center

Amsterdam, The Netherlands

Dirk Fischer, MD

Department of Neuropaediatrics

University Children's Hospital Basel

Basel, Switzerland

Introduction.- Ultrasound.- Computed Tomography.- Conventional MRI.- Advanced and Quantitative MRI Techniques.- Nuclear Medicine Methods.- Peripheral Nerve Imaging.- Introduction.- Morphology of Skeletal Muscle.- Atlas of Topographical Muscle Anatomy.- Normal Ageing Muscle Tissue.- Introduction.- Skeletal Muscle Channelopathies.- Metabolic Myopathies.- Congenital Myopathies.- Congenital Muscular Dystrophies.- Dystrophinopathies.- Emerinopathies and Laminopathies.- Limb Girdle Muscular Dystrophies.- Myofibrillar Myopathies.- Distal Myopathies.- Myotonic Dystrophies.- Facioscapulohumeral Dystrophy.- Oculo-Pharyngeal-Muscular Dystrophy.- Diagnostic Algorithms and Differential Diagnosis.- Inflammatory Myopathies.- Toxic and Drug-Induced Myopathies.- Muscle Neoplasm.- Motor Neuron Diseases.- Clinical Applications of Periperal Nerve Imaging.