Beschreibung
InhaltsangabePart I. Design Strategies for Synthetic Gene Network 1. In silico Implementation of Synthetic Gene Networks Maria Andrea Marchisio 2. Standardization in Synthetic Biology Kristian M. Müller and Katja M. Arndt 3. Robust Optimal Design of Synthetic Biological Networks Dirk Lebiedz, Marcel Rehberg, and Dominik Skanda 4. Predicting Synthetic Gene Networks Diego di Bernardo, Lucia Marucci, Filippo Menolascina, and Velia Siciliano Part II. Development and Characterization of the Synthetic Biology Toolbox 5. Reprogramming a GFP Reporter Gene Subjects it to Complex Lentiviral Gene Regulation Frank Notka and Ralf Wagner 6. A High-throughput Microfluidic Method for Generating and Characterizing Transcription Factor Mutant Libraries Marcel Geertz, Sylvie Rockel, and Sebastian J. Maerkl 7. Identifying and Optimizing Intracellular Protein-protein Interactions using Bacterial Genetic Selection Dujduan Waraho and Matthew P. DeLisa 8. Zinc-finger Nucleases Based Genome Engineering to Generate Isogenic Human Cell Lines Anne-Kathrin Dreyer and Toni Cathomen 9. RNA-based Networks: Using RNA Aptamers and Ribozymes as Synthetic Genetic Devices Julia E. Weigandm Alexander Wittmann, and Beatrix Suess 10. MicroRNA Circuits for Transcriptional Logic Madeleine Leisner, Leonidas Bleris, Jason Lohmueller, Zhen Xie, and Yaakov Benenson 11. Light-regulated Gene Expression in Yeast Laszlo Kozma-Bognar, Anita Hajdu, and Ferenc Nagy 12. Light-controlled Gene Switches in Mammalian Cells Fuzhong Zhang, Kristian M. Müller, G. Andrew Woolley, and Katja M. Arndt 13. Expressed Protein Modifications: Making Synthetic Proteins Birgit Wiltschi Part III. Optimizing the Host Systems 14. Using Transcription Machinery Engineering to Elicit Complex Cellular Phenotypes Amanda M. Lanza and Hal S. Alper 15. Streamlining of a Pseudomonas putida Genome using a Combinatorial Deletion Method Based on Mini-transposon Insertion and the Flp-FRT Recombination System Audrey Leprince, Danielle Janus, Victor de Lorenzo, and Vitor Martins dos Santos 16. Transposon-based and Plasmid-based Genetic Tools for Editing Genomes of Gram-negative Bacteria Esteban Martinez-García and Víctor de Lorenzo Part IV. Implementation of Synthetic Gene Networks in Different Host Systems 17. Synthetic Networks: Oscillators and Toggle Switches for Escherichia coli Nicolas Perry and Alexander J. Ninfa 18. Studying Microbial Communities in Biofilms Katie Brenner 19. Quantitative Analysis of the Spatiotemporal Dynamics of a Synthetic Predator-prey Ecosystem Stephen Payne, Robert Phillip Smith, and Lingchong You 20. Drosophila S2 Schneider Cells - A Useful Tool for Rebuilding and Redesigning Approaches in Synthetic Biology Jianying Yang and Michael Reth 21. Synthetic Gene Networks in Plant Systems Astrid Junker and Björn H. Junker 22. Design and Construction of Synthetic Gene Networks in Mammalian Cells Maria Karlsson, Wilfried Weber, Martin Fussenegger 23. Synthetic Gene Networks as Blueprint for Smart Hydrogels Michael M. Kämpf and Wilfried Weber
Inhalt
Part I. Design Strategies for Synthetic Gene Network 1. In silico Implementation of Synthetic Gene Networks Maria Andrea Marchisio 2. Standardization in Synthetic Biology Kristian M. Müller and Katja M. Arndt 3. Robust Optimal Design of Synthetic Biological Networks Dirk Lebiedz, Marcel Rehberg, and Dominik Skanda 4. Predicting Synthetic Gene Networks Diego di Bernardo, Lucia Marucci, Filippo Menolascina, and Velia Siciliano Part II. Development and Characterization of the Synthetic Biology Toolbox 5. Reprogramming a GFP Reporter Gene Subjects it to Complex Lentiviral Gene Regulation Frank Notka and Ralf Wagner 6. A High-throughput Microfluidic Method for Generating and Characterizing Transcription Factor Mutant Libraries Marcel Geertz, Sylvie Rockel, and Sebastian J. Maerkl 7. Identifying and Optimizing Intracellular Protein-protein Interactions using Bacterial Genetic Selection Dujduan Waraho and Matthew P. DeLisa 8. Zinc-finger Nucleases Based Genome Engineering to Generate Isogenic Human Cell Lines Anne-Kathrin Dreyer and Toni Cathomen 9. RNA-based Networks: Using RNA Aptamers and Ribozymes as Synthetic Genetic Devices Julia E. Weigandm Alexander Wittmann, and Beatrix Suess 10. MicroRNA Circuits for Transcriptional Logic Madeleine Leisner, Leonidas Bleris, Jason Lohmueller, Zhen Xie, and Yaakov Benenson 11. Light-regulated Gene Expression in Yeast Laszlo Kozma-Bognar, Anita Hajdu, and Ferenc Nagy 12. Light-controlled Gene Switches in Mammalian Cells Fuzhong Zhang, Kristian M. Müller, G. Andrew Woolley, and Katja M. Arndt 13. Expressed Protein Modifications: Making Synthetic Proteins Birgit Wiltschi Part III. Optimizing the Host Systems 14. Using Transcription Machinery Engineering to Elicit Complex Cellular Phenotypes Amanda M. Lanza and Hal S. Alper 15. Streamlining of a Pseudomonas putida Genome using a Combinatorial Deletion Method Based on Mini-transposon Insertion and the Flp-FRT Recombination System Audrey Leprince, Danielle Janus, Victor de Lorenzo, and Vitor Martins dos Santos 16. Transposon-based and Plasmid-based Genetic Tools for Editing Genomes of Gram-negative Bacteria Esteban Martinez-GarcÃa and VÃctor de Lorenzo Part IV. Implementation of Synthetic Gene Networks in Different Host Systems 17. Synthetic Networks: Oscillators and Toggle Switches for Escherichia coli Nicolas Perry and Alexander J. Ninfa 18. Studying Microbial Communities in Biofilms Katie Brenner 19. Quantitative Analysis of the Spatiotemporal Dynamics of a Synthetic Predator-prey Ecosystem Stephen Payne, Robert Phillip Smith, and Lingchong You 20. Drosophila S2 Schneider Cells - A Useful Tool for Rebuilding and Redesigning Approaches in Synthetic Biology Jianying Yang and Michael Reth 21. Synthetic Gene Networks in Plant Systems Astrid Junker and Björn H. Junker 22. Design and Construction of Synthetic Gene Networks in Mammalian Cells Maria Karlsson, Wilfried Weber, Martin Fussenegger 23. Synthetic Gene Networks as Blueprint for Smart Hydrogels Michael M. Kämpf and Wilfried Weber