Frontmatter -- Contributors -- Contents -- Introduction -- Role of nitric oxide as a signalling molecule in the cardiovascular system -- From an explosive to the endogenous nitrate: Historical, physiological and clinical aspects -- The role of nitrates in the therapy of congestive heart failure -- Long-term oral treatment with nitrates - what is important? -- Alternatives in long-term nitrate therapy -- The Yin and Yang of nitric oxide, or: the importance of vascular control in acute ischaemia and decrease in cardiac output -- Economic impact of Elantan LA compared to Tenormin and Tildiem LA in the treatment of stable angina in the UK -- Quality of life in angina therapy: focus on the beneficial effects of nitrates -- New trends in interventional cardiology